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CLEVELAND -- Corey Dickerson hit two of Tampa Bay's season-high five home runs, leading the Rays to a 6-4 victory over the Cleveland Indians on Tuesday night.
Dickerson hit solo home runs in the third and fifth off Danny Salazar (2-4). Colby Rasmus and Derek Norris also hit solo shots off Cleveland's starter while Tim Beckham hit a two-run homer off Shawn Armstrong.
Jake Odorizzi (3-2) allowed four runs in six innings. The right-hander took a 6-1 lead into the sixth, but Edwin Encarnacion broke an 0-for-18 skid with a two-run homer to cap a three-run rally.
Jose Alvarado retired all six batters he faced and Alex Colome pitched out of a ninth-inning jam for his 10th save.
Encarnacion led off with a single, but Colome retired Jose Ramirez on a groundout and struck out Lonnie Chisenhall and Yan Gomes.
Indians center fielder Bradley Zimmer was 0-for-3 with three strikeouts in his major league debut. Cleveland called up its No. 1 pick in 2014 from Triple-A Columbus earlier Tuesday.
The Rays won despite striking out 16 times.
Rasmus homered with two outs in the second while Norris and Dickerson went back-to-back to start the third. Dickerson cleared the wall in center to lead off the fifth for his fifth career two-homer game, a drive that landed in the trees and traveled an estimated 449 feet.
Beckham's sixth-inning home run pushed the lead to 6-1.
After using five relievers in Monday's win, the Indians needed Salazar to pitch deep into the game, but he was pulled following a leadoff double in the sixth. The right-hander was charged with five runs and struck out nine in five-plus innings.
Salazar was coming off a shaky outing against Toronto, in which he couldn't hold two early leads and allowed five runs in 2 2/3 innings. He hasn't won since April 29.
Rays: 2B Brad Miller (strained left abdominal muscle) was scratched about two hours before the game.
Indians: RHP Carlos Carrasco (strained left pectoral muscle) will resume his between starts routine in a couple of days. He's scheduled to start again on May 23 against Cincinnati.
Rays: RHP Alex Cobb is 2-2 in four regular-season starts against Cleveland. He pitched 6 2/3 scoreless innings and got the win in the 2013 AL Wild Card game at Progressive Field
Indians: RHP Josh Tomlin was the losing pitcher in his last start against Minnesota, despite allowing only Miguel Sano's solo homer in eight innings.
INDIANS CALL UP TOP PROSPECT ZIMMER
Bradley Zimmer was taking an ice bath after a minor league game when he got word his manager wanted to see him.
With no time to dry off Monday night, the top prospect in the Cleveland Indians' organization threw on some workout clothes and went to see Chris Tremie, the manager at Triple-A Columbus.
The news was unexpected. The 24-year-old would be joining the defending AL champions.
"Honestly it's hard to put into words what that moment was," he said. "It's something I'll never forget."
Zimmer called his parents, who traveled in from California to watch his major league debut against Tampa Bay on Tuesday night. The Indians' first-round draft pick in 2014 batted ninth and played center field.
Zimmer also called his brother, Kyle, who is pitching at Triple-A Omaha. Kyle Zimmer was the Kansas City Royals' No. 1 pick in 2012.
Trying to get some rest proved to be Zimmer's biggest challenge before the two-hour drive to Cleveland on Tuesday morning.
"It was tough at first because it was so exciting," he said. "Once I settled in and packed, I was able to get some sleep. I'm treating it like another day. I was supposed to be in the lineup at Columbus and instead I'm in Cleveland."
Zimmer was hitting .294 with five home runs and 14 RBI in 33 games with Columbus.
The Indians have been dealing with several injuries this month. Right-hander Carlos Carrasco was removed from Monday's game because of a strained left pectoral muscle and will have his next start pushed back to May 23 in Cincinnati.
Outfielder Abraham Almonte was put on the 10-day disabled list with a strained right biceps. Almonte injured his arm during an at-bat last week. He started in right field Monday but was removed in the fifth inning. Almonte is batting .221 with one homer and six RBI in 33 games.
Right-hander Corey Kluber (strained lower back) and outfielders Austin Jackson (sprained left toe) and Brandon Guyer (sprained left wrist) are also on the 10-day DL.